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J. Biochem, 1988, Vol. 103, No. 6 905-906
© 1988 Japanese Biochemical Society

other

Crystallization and Preliminary X-Ray Studies on Human Epidermal Growth Factor

Yoshiki Higuchi*, Yukio Morimoto*, Akio Horinaka** and Noritake Yasuoka*,1

*Basic Research Laboratory, Himeji Institute of Technology Himeji, Hyogo 671-22
**Research Laboratories, Earth Chemical Co., Ltd., Ako, Hyogo 678-01

1To whom correspondence should be addressed.

Single crystals of human epidermal growth factor have been prepared from a polyethylene glycol solution and characterized by X-ray diffraction. The crystals grow in a space group of P2, with unit cell dimensions of a=32.7, b=32.5, c=22.3 Å, and ß=96.9°. They contain a single molecule per asymmetric unit and show better diffraction than 2.5 Å.


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H.-S. Lu, J.-J. Chai, M. Li, B.-R. Huang, C.-H. He, and R.-C. Bi
Crystal Structure of Human Epidermal Growth Factor and Its Dimerization
J. Biol. Chem., September 7, 2001; 276(37): 34913 - 34917.
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