Skip Navigation

Journal of Biochemistry 2005 138(1):5-12; doi:10.1093/jb/mvi097
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Yao, H. H-C
Right arrow Articles by Capel, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yao, H. H-C
Right arrow Articles by Capel, B.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2005 The Japanese Biochemical Society

JB Minireview

Temperature, Genes, and Sex: a Comparative View of Sex Determination in Trachemys scripta and Mus musculus

Humphrey H-C Yao1 and Blanche Capel2,*

1 Department of Veterinary Biosciences, University of Illinois at Urbana-Champaign; and 2 Department of Cell Biology, Duke University Medical Center

* To whom correspondence should be addressed at: 4026 GSRBII, Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA. Tel: +1-919-684-6390, Fax: +1-919-668-3467, E-mail: b.capel{at}cellbio.duke.edu

Sex determination, the step at which differentiation of males and females is initiated in the embryo, is of central importance to the propagation of species. There is a remarkable diversity of mechanisms by which sex determination is accomplished. In general these mechanisms fall into two categories: Genetic Sex Determination (GSD), which depends on genetic differences between the sexes, and Environmental Sex Determination (ESD), which depends on extrinsic cues. In this review we will consider these two means of determining sex with particular emphasis on two species: a species that depends on GSD, Mus musculus, and a species that depends on ESD, Trachemys scripta. Because the structural organization of the adult testis and ovary is very similar across vertebrates, most biologists had expected that the pathways downstream of the sex-determining switch would be conserved. However, emerging data indicate that not only are the initial sex determining mechanisms different, but the downstream pathways and morphogenetic events leading to the development of a testis or ovary also are different.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Integr. Comp. Biol.Home page
S. Kohno, Y. Katsu, T. Iguchi, and L. J. Guillette Jr
Novel approaches for the study of vertebrate steroid hormone receptors
Integr. Comp. Biol., October 1, 2008; 48(4): 527 - 534.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Endocrinol.Home page
L. DiNapoli and B. Capel
SRY and the Standoff in Sex Determination
Mol. Endocrinol., January 1, 2008; 22(1): 1 - 9.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
A. Shirak, E. Seroussi, A. Cnaani, A. E. Howe, R. Domokhovsky, N. Zilberman, T. D. Kocher, G. Hulata, and M. Ron
Amh and Dmrta2 Genes Map to Tilapia (Oreochromis spp.) Linkage Group 23 Within Quantitative Trait Locus Regions for Sex Determination
Genetics, November 1, 2006; 174(3): 1573 - 1581.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.