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J. Biochem, 1982, Vol. 91, No. 6 2067-2075
© 1982 Japanese Biochemical Society

research-article

Fractionation and Characterization of Basic Proline-Rich Peptides of Human Parotid Saliva and the Amino Acid Sequence of Proline-Rich Peptide P-E

Satoko ISEMURA, Eiichi SAITOH and Kazuo SANADA

Department of Oral Biochemistry, Nippon Dental University Niigata Faculty Niigata, Niigata 951

Basic proline-rich peptides of human parotid saliva were fractionated and characterized. The amino acid sequence of one of the purified peptides, P-E, was determined to be SPPGKPQGPFormulaPQGGNQPQGFormulaPPPPGKPQGFormulaPPQGGNRPQFormulaPPPPGKPQGFormulaPPQGDKSRSFormulaR.

The results demonstrate the repetitiveness of the partial sequence within the molecule and the occurrence of structures common to those of other salivary poly-peptides such as P-C and Protein C.


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