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Journal of Biochemistry Advance Access published online on April 6, 2007
Journal of Biochemistry, doi:10.1093/jb/mvm092
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© 2007 The Japanese Biochemical Society

JB Minireview

Crucial roles for chromatin dynamics in cellular memory

Susumu Hirose

Department of Developmental Genetics, National Institute of Genetics, and Department of Genetics, SOKENDAI

Corresponding author: Susumu Hirose, 1111 Mishima, Shizuoka-ken 411-8540, National Institute of Genetics; Phone number: +81-55-981-6771; Fax number: +81-55-981-6776, E-mail address: shirose{at}lab.nig.ac.jp

Received January 18, 2007; Accepted February 28, 2007


  Abstract

Cellular memory is defined as a long term maintenance of a particular pattern of gene expression through many rounds of cell division or even after cell division. It is critical for development and differentiation of multicellular organisms. Chromatin dynamics including histone modification, histone replacement and chromatin remodeling play key roles in cellular memory.

Key Words: Pc group, trx group, position effect variegation, heterochromatin, histone H3.3


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 Learn. Mem.Home page
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[Abstract] [Full Text] [PDF]


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